Uptown - Upper Duval, FL

Key West

Key West Butterfly and Nature Conservatory featuring zoo animals, animals and flowers
Key West Butterfly and Nature Conservatory showing zoo animals, animals and flowers
South Beach which includes a beach and a coastal town as well as a large group of people
South Beach showing a beach, swimming and a luxury hotel or resort
Key West Butterfly and Nature Conservatory featuring signage

Popular places to visit

Southernmost Point featuring signage as well as a large group of people

Southernmost Point

4.5/5(3,182 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach featuring a sandy beach and general coastal views as well as a small group of people

South Beach

4/5(980 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory showing animals, zoo animals and food

Key West Butterfly and Nature Conservatory

4.5/5(760 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is ₩638,581 per night from May 5 to May 6
₩638,581
₩816,356 total
includes taxes & fees
May 5 - May 6
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,380 reviews)
"I really enjoyed my long weekend at the Southernmost Beach Resort. There are several pools, beaches, bars and a restaurant. My room was clean and spacious. All the staff I encountered were super friendly. Great location and easy walking distance to Duval."

Reviewed on Apr 1, 2025

Southernmost Beach Resort
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is ₩529,104 per night from May 5 to May 6
₩529,104
₩682,301 total
includes taxes & fees
May 5 - May 6
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (913 reviews)
"Liked the beach area."

Reviewed on Mar 31, 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is ₩346,787 per night from Apr 7 to Apr 8
₩346,787
₩455,415 total
includes taxes & fees
Apr 7 - Apr 8
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8/10 Very Good! (1,033 reviews)
"Very personal staff, helpful and informative. Our last minute need for a night proved to be a great option."

Reviewed on Apr 3, 2025

The Southernmost Inn - Adults Only
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
Fully refundable
The price is ₩324,850 per night from Apr 29 to Apr 30
₩324,850
₩406,595 total
includes taxes & fees
Apr 29 - Apr 30
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,091 reviews)
Key West
"Clean and wonderful location"

Reviewed on Apr 1, 2025

Southwinds Motel
Douglas House
Douglas House
3 out of 5
419 Amelia St, Key West, FL
The price is ₩329,526 per night from Apr 20 to Apr 21
₩329,526
₩383,692 total
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ...
9.4/10 Exceptional! (54 reviews)
"This was a total last minute find and WOW did Douglas House impress. This two bedroom suite was perfectly located and appointed. And the HUGE wrap-around balcony was the perfect spot to take in Duval St. Far enough away so it's quiet, but two blocks to walk to the action or to the water."

Reviewed on Mar 31, 2025

Douglas House
Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only
3.5 out of 5
1004 Duval St, Key West, FL
The price is ₩578,903 per night from Apr 7 to Apr 8
₩578,903
₩651,266 total
includes taxes & fees
Apr 7 - Apr 8
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
9.8/10 Exceptional! (990 reviews)
"Location is great! Our stay was perfect!"

Reviewed on Apr 2, 2025

Orchid Key Inn - Adults Only
See all 2,853 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

4.5/5(226 area reviews)

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

Old Town Key West
Key West featuring a marina, a coastal town and general coastal views

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

5/5(38 area reviews)

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Clarence S. Higgs Memorial Beach Park which includes landscape views, tropical scenes and a sandy beach

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

4.5/5(4,033 area reviews)

Old Town Key West boasts a rich history with 2485 historic buildings, and is home to popular attractions like Ernest Hemingway House and Mallory Square. Enjoy the lively atmosphere in the central business district.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Saint Mary Star of the Sea, some noteworthy sights in the nearby area.

White Street Gallery District

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