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Find hotels in South Main, Houston from ₩109,310

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Discover 6,308 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

The Whitehall Houston
City view from property

The Whitehall Houston

4.0 star property
8.4 out of 10, Very Good, (1142)
"Very clean vey respectfull "
The price is ₩183,509
₩214,706 total
includes taxes & fees
Jan 5 - Jan 6, 2025
The Whitehall Houston
Holiday Inn Houston Downtown, an IHG Hotel
Property amenity

Holiday Inn Houston Downtown, an IHG Hotel

3.0 star property
8.6 out of 10, Excellent, (1014)
"Housekeeping was amazing "
The price is ₩109,310
₩153,251 total
includes taxes & fees
Dec 26 - Dec 27
Holiday Inn Houston Downtown, an IHG Hotel
Blossom Hotel Houston
City view

Blossom Hotel Houston

4.0 star property
9.2 out of 10, Wonderful, (2975)
"Thanks for a nice stay. :)"
The price is ₩184,776
₩216,189 total
includes taxes & fees
Jan 2 - Jan 3, 2025
Blossom Hotel Houston
Club Quarters Hotel Downtown, Houston
Exterior

Club Quarters Hotel Downtown, Houston

4.0 star property
8.2 out of 10, Very Good, (3087)
"We had a wonderful stay and would stay again!"
The price is ₩140,016
₩163,819 total
includes taxes & fees
Dec 24 - Dec 25
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.0 out of 10, Very Good, (1637)
"Overall great experience "
The price is ₩172,238
₩202,919 total
includes taxes & fees
Jan 2 - Jan 3, 2025
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Marriott Marquis Houston
2 outdoor pools, open 6:00 AM to 10:00 PM, cabanas (surcharge)

Marriott Marquis Houston

4.0 star property
8.8 out of 10, Excellent, (1005)
"I enjoyed my stay. There is many restaurants and bars in walking distance. "
The price is ₩281,260
₩377,828 total
includes taxes & fees
Dec 26 - Dec 27
Marriott Marquis Houston
Hilton Americas-Houston
Exterior

Hilton Americas-Houston

4.0 star property
9.2 out of 10, Wonderful, (1166)
"This Hilton was clean and in a great location to walk to many things. We enjoyed the view overlooking the green space and would stay here again. "
The price is ₩215,962
₩256,059 total
includes taxes & fees
Jan 1 - Jan 2, 2025
Hilton Americas-Houston
C. Baldwin, Curio Collection by Hilton
Outdoor banquet area

C. Baldwin, Curio Collection by Hilton

4.0 star property
8.4 out of 10, Very Good, (957)
"No microwave or fridge "
The price is ₩218,476
₩293,910 total
includes taxes & fees
Dec 25 - Dec 26
C. Baldwin, Curio Collection by Hilton
Hyatt Place Houston Medical Center
Lobby

Hyatt Place Houston Medical Center

3.0 star property
9.0 out of 10, Wonderful, (1246)
"Good "
The price is ₩158,439
₩186,356 total
includes taxes & fees
Dec 23 - Dec 24
Hyatt Place Houston Medical Center
Hyatt Place Houston Downtown
Lobby sitting area

Hyatt Place Houston Downtown

3.0 star property
9.0 out of 10, Wonderful, (1406)
"This was the second time that we have stayed here and both times it was for a concert that was in town. The hotel was close to the venue, so it was an excellent choice!"
The price is ₩170,721
₩203,443 total
includes taxes & fees
Dec 23 - Dec 24
Hyatt Place Houston Downtown
Hyatt Regency Houston Downtown
City view

Hyatt Regency Houston Downtown

4.0 star property
9.2 out of 10, Wonderful, (1002)
"The hotel was wonderful, the staff were very helpful and attentive."
The price is ₩244,197
₩294,597 total
includes taxes & fees
Dec 23 - Dec 24
Hyatt Regency Houston Downtown
Cambria Hotel Houston Downtown Convention Center
Lobby

Cambria Hotel Houston Downtown Convention Center

3.0 star property
8.8 out of 10, Excellent, (1424)
"My partner and I visited Houston and enjoyed our stay at the Cambria. So modern, upbeat, clean and overall just great! Staff were very kind and food was delicious! Favorite hotel in Houston now! "
The price is ₩143,050
₩167,368 total
includes taxes & fees
Dec 23 - Dec 24
Cambria Hotel Houston Downtown Convention Center
Rusk House Serviced Apartments
Check-in/check-out kiosk

Rusk House Serviced Apartments

4.5 star property
9.2 out of 10, Wonderful, (103)
"Awesome friendly staff, beautiful rooms, valet easy. Definitely will book again."
The price is ₩187,844
₩219,777 total
includes taxes & fees
Dec 28 - Dec 29
Rusk House Serviced Apartments
Hilton Houston Plaza/Medical Center
Sundeck

Hilton Houston Plaza/Medical Center

3.5 star property
8.2 out of 10, Very Good, (1097)
"The kids and us loved it. They accommodated everything we needed "
The price is ₩114,151
₩135,234 total
includes taxes & fees
Dec 23 - Dec 24
Hilton Houston Plaza/Medical Center
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.2 out of 10, Very Good, (1007)
"The staff went above and beyond for me. I had gotten sick when I was staying there and they accommodated my needs to help me recover .... the chef made me something I could eat. Dennis at the Front Desk was wonderful. Martin delivered things I needed as well as Dennis. The hotel manager, assisted in my recovery. I would highly recommend this hotel. I also loved how safe I felt staying here. "
The price is ₩206,628
₩278,948 total
includes taxes & fees
Jan 3 - Jan 4, 2025
The Royal Sonesta Houston Galleria
Le Meridien Houston Downtown
Rooftop terrace

Le Meridien Houston Downtown

4.0 star property
8.6 out of 10, Excellent, (876)
"should definitely have more than two people for valet "
The price is ₩218,476
₩255,617 total
includes taxes & fees
Dec 24 - Dec 25
Le Meridien Houston Downtown
Moxy Houston Downtown
Front of property - evening/night

Moxy Houston Downtown

3.0 star property
9.0 out of 10, Wonderful, (293)
"Close to a lot of restaurants and bars, parking is close by."
The price is ₩137,270
₩163,497 total
includes taxes & fees
Dec 24 - Dec 25
Moxy Houston Downtown
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers

Hyatt Regency Houston/Galleria

4.0 star property
8.8 out of 10, Excellent, (1007)
"Nice"
The price is ₩167,758
₩197,954 total
includes taxes & fees
Jan 4 - Jan 5, 2025
Hyatt Regency Houston/Galleria
The Post Oak Hotel at Uptown Houston
Outdoor pool, cabanas (surcharge), pool umbrellas

The Post Oak Hotel at Uptown Houston

5.0 star property
9.6 out of 10, Exceptional, (678)
"Best hotel in Houston 5 stars!!"
The price is ₩806,282
₩943,350 total
includes taxes & fees
Jan 5 - Jan 6, 2025
The Post Oak Hotel at Uptown Houston
The Chifley Houston, Tapestry Collection by Hilton
Lobby

The Chifley Houston, Tapestry Collection by Hilton

4.0 star property
8.8 out of 10, Excellent, (1008)
"A well-located and well-priced alternative for this busy area of Houston. The facilities are new and well-maintained."
The price is ₩214,936
₩251,475 total
includes taxes & fees
Dec 25 - Dec 26
The Chifley Houston, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 66 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.