Photo by Hazem Abdul

Find hotels in South Main, Houston from ₩110,805

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Discover 6,180 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Club Quarters Hotel Downtown, Houston
4.0 star property
8.2 out of 10, Very Good, (3071)
"Hmmmm"
The price is ₩127,594
₩149,285 total
includes taxes & fees
Dec 21 - Dec 22
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
8.0 out of 10, Very Good, (1575)
"The location of this hotel is ideal for many activities in town . They've kept the hotel but the age definitely shows .we stayed in a king suite great space if you have a little one . There was a few cockroaches wich is expected witha kitchenette. The only down side was the elevator situation ,as they had 2 of the 4 elevators down and weekends are very busy at this location wich made for a 15-20 wait especially if you are on the top floors we were on the 20th. They also had maintenance ...
The price is ₩141,752
₩167,009 total
includes taxes & fees
Dec 20 - Dec 21
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston
4.0 star property
8.4 out of 10, Very Good, (1077)
"Excellent service "
The price is ₩160,051
₩187,261 total
includes taxes & fees
Dec 2 - Dec 3
The Whitehall Houston
Blossom Hotel Houston
4.0 star property
9.2 out of 10, Wonderful, (2870)
"Friendly staff, super clean, food was great, no complaints. "
The price is ₩189,151
₩221,307 total
includes taxes & fees
Nov 26 - Nov 27
Blossom Hotel Houston
Holiday Inn Houston Downtown, an IHG Hotel
3.0 star property
8.6 out of 10, Excellent, (1004)
"Very clean! "
The price is ₩118,919
₩163,689 total
includes taxes & fees
Dec 20 - Dec 21
Holiday Inn Houston Downtown, an IHG Hotel
Marriott Marquis Houston
4.0 star property
8.8 out of 10, Excellent, (1006)
"Stuff"
The price is ₩313,387
₩414,439 total
includes taxes & fees
Dec 22 - Dec 23
Marriott Marquis Houston
Hilton Americas-Houston
4.0 star property
9.2 out of 10, Wonderful, (1121)
"I enjoyed the people and the amazing things offered. Thank you for your service I am happy I was able to relax and enjoy myself."
The price is ₩214,055
₩253,719 total
includes taxes & fees
Dec 22 - Dec 23
Hilton Americas-Houston
Hyatt Regency Houston Downtown
4.0 star property
9.2 out of 10, Wonderful, (1005)
"Good "
The price is ₩212,795
₩257,576 total
includes taxes & fees
Dec 19 - Dec 20
Hyatt Regency Houston Downtown
C. Baldwin, Curio Collection by Hilton
4.0 star property
8.4 out of 10, Very Good, (925)
"I loved this property and the surrounding neighborhood. The decor and artwork in the lobby were top notch. I was very happy with the comfort of the bed and the staff was attentive. I'd definitely coming back."
The price is ₩197,878
₩268,412 total
includes taxes & fees
Nov 26 - Nov 27
C. Baldwin, Curio Collection by Hilton
Hyatt Place Houston Medical Center
3.0 star property
9.0 out of 10, Wonderful, (1172)
"Good service and consistent location. "
The price is ₩161,640
₩190,122 total
includes taxes & fees
Nov 26 - Nov 27
Hyatt Place Houston Medical Center
Rusk House Serviced Apartments
4.5 star property
9.2 out of 10, Wonderful, (84)
"Would definitely stay again! The staff was accommodating, check in process was seamless, and the room was great. There were a couple of small things that I did not like, but the good outweighed the bad tenfold. Next time I’m in Houston, I’m staying here!"
The price is ₩194,915
₩228,052 total
includes taxes & fees
Nov 28 - Nov 29
Rusk House Serviced Apartments
Hyatt Place Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (1395)
"Azur and Nay were amazing. They were very helpful. Azur went the extra mile To make sure we were accommodated and comfortable. He had an amazing presence and energy. May remembered me from questions I asked her on the phone when I checked in. That says alot about the attention to detail. Great stay. Room was very clean. Only issue we had was the hallway by the ice machine smelled like urine. Other than that I give the stay 5 stars! "
The price is ₩183,429
₩218,176 total
includes taxes & fees
Nov 26 - Nov 27
Hyatt Place Houston Downtown
Cambria Hotel Houston Downtown Convention Center
3.0 star property
8.8 out of 10, Excellent, (1427)
"Loved the coffee vendor at the front door every morning. The regular guy that works in the mornings is a great person. Really enjoyed talking to him"
The price is ₩152,006
₩177,847 total
includes taxes & fees
Dec 22 - Dec 23
Cambria Hotel Houston Downtown Convention Center
Le Meridien Houston Downtown
4.0 star property
8.6 out of 10, Excellent, (867)
"Decent hotel with excellent staff. Bed wasn’t very comfortable, but otherwise a good stay. "
The price is ₩211,536
₩247,498 total
includes taxes & fees
Nov 24 - Nov 25
Le Meridien Houston Downtown
Crowne Plaza Houston Med Ctr-Galleria Area, an IHG Hotel
3.5 star property
7.4 out of 10, Good, (1003)
"Nice, updated, enjoyed my stay "
The price is ₩114,401
₩133,848 total
includes taxes & fees
Nov 26 - Nov 27
Crowne Plaza Houston Med Ctr-Galleria Area, an IHG Hotel
The Post Oak Hotel at Uptown Houston
5.0 star property
9.6 out of 10, Exceptional, (674)
"Amazing service, great quality "
The price is ₩776,876
₩908,944 total
includes taxes & fees
Dec 17 - Dec 18
The Post Oak Hotel at Uptown Houston
Moxy Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (263)
"I really liked the hotel. Great for young professionals. Bartenders were awesome with good recommendations for nightlife. Would definitely stay there again"
The price is ₩110,805
₩132,441 total
includes taxes & fees
Nov 24 - Nov 25
Moxy Houston Downtown
The Chifley Houston, Tapestry Collection by Hilton
4.0 star property
8.8 out of 10, Excellent, (1003)
"Great location. Walking distance to Galleria Mall. Friendly staff. Reasonable parking rates. Definitely recommend for staying in the Loop. "
The price is ₩207,097
₩242,303 total
includes taxes & fees
Nov 25 - Nov 26
The Chifley Houston, Tapestry Collection by Hilton
The Royal Sonesta Houston Galleria
4.0 star property
8.2 out of 10, Very Good, (1006)
"Stay was great! Carpet needs replacing in the rooms."
The price is ₩237,978
₩314,446 total
includes taxes & fees
Dec 2 - Dec 3
The Royal Sonesta Houston Galleria
InterContinental Houston, an IHG Hotel
4.0 star property
9.2 out of 10, Wonderful, (1005)
"I like everything!"
The price is ₩187,473
₩240,329 total
includes taxes & fees
Dec 20 - Dec 21
InterContinental Houston, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 68 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.