Find Resorts & Hotels with Spas in Panama City

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Pick from 49 Panama City Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
8.8 out of 10, Excellent, (885)
"I will definitely stay here again. The staff went beyond the call of duty to help non spanish speaking customers"
The price is ₩208,458
₩229,304 total
includes taxes & fees
Dec 8 - Dec 9
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Exterior
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (514)
"Beautiful resort with very helpful and friendly staff. The food was amazing! I’ll definitely be back."
The price is ₩236,439
₩260,083 total
includes taxes & fees
Dec 13 - Dec 14
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Marriott Panama Hotel
Terrace/patio
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1000)
"I really enjoyed my time at the Marriott and im looking forward to coming back soon "
The price is ₩201,797
₩221,977 total
includes taxes & fees
Dec 21 - Dec 22
Marriott Panama Hotel
Bristol Panama, a Registry Collection Hotel
Couples treatment rooms, steam room, Turkish bath, body treatments
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"It is a great hotel, with great staff and superb personalized service. Totally recommended!"
The price is ₩238,233
₩262,056 total
includes taxes & fees
Dec 21 - Dec 22
Bristol Panama, a Registry Collection Hotel
W Panama
Marvelous Suite, Suite, 1 King Bed, Non Smoking, City View | In-room safe, blackout drapes, iron/ironing board
W Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Lo único que puedo decir es que el baño mejor la ducha tiene moho. Todo lo demás estuvo muy lindo y bueno"
The price is ₩178,254
₩196,079 total
includes taxes & fees
Dec 20 - Dec 21
W Panama
Sofitel Legend Casco Viejo, Panama City
Exterior
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (337)
"Very clean and the staff was very friendly and helpful always checking to see how they could improve my wonderful experience "
The price is ₩409,901
₩450,891 total
includes taxes & fees
Dec 19 - Dec 20
Sofitel Legend Casco Viejo, Panama City
Sheraton Grand Panama
Outdoor pool, pool umbrellas, sun loungers
Sheraton Grand Panama
4.0 star property
8.4 out of 10, Very Good, (816)
"The front desk staff was extremely hepful with suggestions of local tours and experiences. They were also quite thoughtful- sent a birthday cake to my mom's room. They added joy to our overall experience "
The price is ₩190,970
₩210,067 total
includes taxes & fees
Nov 23 - Nov 24
Sheraton Grand Panama
Hilton Panama
Outdoor pool
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1003)
"The hotel was modern and well maintained. Staff were friendly and helpful. Loved how central it was and close to everything."
The price is ₩189,152
₩208,067 total
includes taxes & fees
Dec 13 - Dec 14
Hilton Panama
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Would visit again"
The price is ₩211,536
₩232,690 total
includes taxes & fees
Dec 7 - Dec 8
JW Marriott Panama
Aloft Panama
Exterior
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (763)
"Beautiful. Great. 10/10. Had a cancelled flight and this was great and I’m a really great area. I’d stay here again for a couple of nights. "
The price is ₩171,384
₩188,522 total
includes taxes & fees
Nov 24 - Nov 25
Aloft Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a rooftop terrace. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Decapolis Hotel Panama City and Las Americas Golden Tower Panama.
How many spa hotels are there in Panama City?
Expedia has 19 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Multicentro Panama.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.