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Find All Southern Illinois Hotels
We have found 966 Southern Illinois Hotels
- Drury Inn & Suites St. Louis O'Fallon, IL
- Red Lion Inn & Suites Pontoon Beach
- Baymont by Wyndham Marion
- Walker's Bluff Casino Resort
- Drury Inn & Suites Marion
- Best Western St. Louis Fairview Heights
- Harrah's Metropolis Hotel & Casino
- Radisson Hotel Fairview Heights - St. Louis
- Comfort Inn & Suites Marion I-57
- Best Western Marion Hotel
- Super 8 by Wyndham Carbondale
- Best Western Saluki Inn
- Home2 Suites by Hilton Carbondale
- Quality Inn Effingham
- Seasons Inn & Suites Highland
- Fairgrounds Inn
- The Principal Hotel
- Suite Dreams Hotel
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.