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Find All Southern Illinois Hotels
We have found 981 Southern Illinois Hotels
- Best Western St. Louis Fairview Heights
- Drury Inn & Suites Marion
- Drury Inn & Suites St. Louis O'Fallon, IL
- Baymont by Wyndham Marion
- Red Lion Inn & Suites Pontoon Beach
- Walker's Bluff Casino Resort
- Radisson Hotel Fairview Heights - St. Louis
- Super 8 by Wyndham Carbondale
- Best Western Saluki Inn
- Seasons Inn & Suites Highland
- Best Western Marion Hotel
- Comfort Inn & Suites Marion I-57
- Harrah's Metropolis Hotel & Casino
- Days Inn by Wyndham Salem, Illinois
- Quality Inn Effingham
- Home2 Suites by Hilton Carbondale
- The Principal Hotel
- Fairgrounds Inn
- Suite Dreams Hotel
- University Inn of Carbondale
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.